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Research Article

Plasma Cholesterol–Induced Lesion Networks Activated before Regression of Early, Mature, and Advanced Atherosclerosis

  • Johan L. M. Björkegren,

    Affiliations: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, Cardiovascular Genomics Group, Department of Pathological Anatomy and Forensic Medicine, University of Tartu, Tartu, Estonia, Institute for Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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  • Sara Hägg,

    Affiliations: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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  • Husain A. Talukdar equal contributor,

    equal contributor Contributed equally to this work with: Husain A. Talukdar, Hassan Foroughi Asl

    Affiliation: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Hassan Foroughi Asl equal contributor,

    equal contributor Contributed equally to this work with: Husain A. Talukdar, Hassan Foroughi Asl

    Affiliation: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Rajeev K. Jain,

    Affiliation: Cardiovascular Genomics Group, Department of Pathological Anatomy and Forensic Medicine, University of Tartu, Tartu, Estonia

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  • Cecilia Cedergren,

    Affiliation: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Ming-Mei Shang,

    Affiliation: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Aránzazu Rossignoli,

    Affiliation: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Rabbe Takolander,

    Affiliation: Department of Surgery, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

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  • Olle Melander,

    Affiliation: Department of Clinical Sciences, Hypertension & Cardiovascular Disease, Clinical Research Centre, Skåne University Hospital, Malmö, Sweden

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  • Anders Hamsten,

    Affiliation: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

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  • Tom Michoel,

    Affiliations: Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, Freiburg, Germany, The Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom

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  • Josefin Skogsberg mail

    Josefin.Skogsberg@ki.se

    Affiliation: Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Published: February 27, 2014
  • DOI: 10.1371/journal.pgen.1004201

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