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Research Article

Synergistic Interaction of Rnf8 and p53 in the Protection against Genomic Instability and Tumorigenesis

  • Marie-Jo Halaby,

    Affiliation: Department of Medical Biophysics, University of Toronto and Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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  • Anne Hakem,

    Affiliation: Department of Medical Biophysics, University of Toronto and Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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  • Li Li,

    Affiliation: Department of Medical Biophysics, University of Toronto and Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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  • Samah El Ghamrasni,

    Affiliation: Department of Medical Biophysics, University of Toronto and Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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  • Shriram Venkatesan,

    Affiliation: Department of Physiology, Yong Loo Lin School of Medicine and Tembusu College, National University of Singapore, Singapore, Singapore

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  • Prakash M. Hande,

    Affiliation: Department of Physiology, Yong Loo Lin School of Medicine and Tembusu College, National University of Singapore, Singapore, Singapore

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  • Otto Sanchez,

    Affiliation: University of Ontario Institute of Technology, Oshawa, Ontario, Canada

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  • Razqallah Hakem mail

    rhakem@uhnres.utoronto.ca

    Affiliation: Department of Medical Biophysics, University of Toronto and Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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  • Published: January 31, 2013
  • DOI: 10.1371/journal.pgen.1003259

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