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Research Article

The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove

  • Minzhong Tang,

    Affiliations: College of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, China, Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America, Wuzhou Health System Key Laboratory for Nasopharyngeal Carcinoma Etiology and Molecular Mechanism, Wuzhou Red Cross Hospital, Guangxi, China

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  • James A. Lautenberger,

    Affiliation: BSP-CCR Genetics Core, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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  • Xiaojiang Gao,

    Affiliations: Cancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC-Frederick, Frederick National Lab, Frederick, Maryland United States of America, Ragon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, United States of America

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  • Efe Sezgin,

    Affiliation: Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America

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  • Sher L. Hendrickson,

    Affiliation: Department of Biology, Shepherd University, Shepherdstown, West Virginia, United States of America

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  • Jennifer L. Troyer,

    Affiliation: Laboratory of Genomic Diversity, SAIC–Frederick, NCI–Frederick, Frederick, Maryland, United States of America

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  • Victor A. David,

    Affiliation: Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America

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  • Li Guan,

    Affiliation: Laboratory of Genomic Diversity, SAIC–Frederick, NCI–Frederick, Frederick, Maryland, United States of America

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  • Carl E. Mcintosh,

    Affiliation: Laboratory of Genomic Diversity, SAIC–Frederick, NCI–Frederick, Frederick, Maryland, United States of America

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  • Xiuchan Guo,

    Affiliations: Laboratory of Genomic Diversity, SAIC–Frederick, NCI–Frederick, Frederick, Maryland, United States of America, State Key Laboratory for Infectious Diseases Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

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  • Yuming Zheng,

    Affiliation: Wuzhou Health System Key Laboratory for Nasopharyngeal Carcinoma Etiology and Molecular Mechanism, Wuzhou Red Cross Hospital, Guangxi, China

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  • Jian Liao,

    Affiliation: Department of Epidemiology, Cangwu Institute for Nasopharyngeal Carcinoma Control and Prevention, Guangxi, China

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  • Hong Deng,

    Affiliation: Wuzhou Health System Key Laboratory for Nasopharyngeal Carcinoma Etiology and Molecular Mechanism, Wuzhou Red Cross Hospital, Guangxi, China

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  • Michael Malasky,

    Affiliation: Laboratory of Genomic Diversity, SAIC–Frederick, NCI–Frederick, Frederick, Maryland, United States of America

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  • Bailey Kessing,

    Affiliation: BSP-CCR Genetics Core, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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  • Cheryl A. Winkler,

    Affiliation: Laboratory of Genomic Diversity, SAIC–Frederick, NCI–Frederick, Frederick, Maryland, United States of America

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  • Mary Carrington,

    Affiliation: Cancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC-Frederick, Frederick National Lab, Frederick, Maryland United States of America

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  • Guy dé The,

    Affiliation: Oncogenic Virus Epidemiology and Pathophysiology, Institute Pasteur, Paris, France

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  • Yi Zeng mail,

    zengy@public.bta.net.cn (Y Zeng); lgdchief@gmail.com (SJ O'Brien)

    Affiliations: College of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, China, State Key Laboratory for Infectious Diseases Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

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  • Stephen J. O'Brien mail

    zengy@public.bta.net.cn (Y Zeng); lgdchief@gmail.com (SJ O'Brien)

    Affiliation: Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America

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  • Published: November 29, 2012
  • DOI: 10.1371/journal.pgen.1003103

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