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Research Article

S Phase–Coupled E2f1 Destruction Ensures Homeostasis in Proliferating Tissues

  • Jean M. Davidson,

    Affiliation: Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Robert J. Duronio mail

    duronio@med.unc.edu

    Affiliations: Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Program in Molecular Biology and Biotechnology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Published: August 16, 2012
  • DOI: 10.1371/journal.pgen.1002831

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It's All in the Timing: Too Much E2F Is a Bad Thing

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doi:10.1371/journal.pgen.1002909