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Research Article

Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency

  • Wenfeng Qian,

    Affiliation: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Jian-Rong Yang,

    Affiliations: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China

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  • Nathaniel M. Pearson,

    Affiliation: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    Current address: Knome, Cambridge, Massachusetts, United States of America

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  • Calum Maclean,

    Affiliation: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Jianzhi Zhang mail

    jianzhi@umich.edu

    Affiliation: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Published: March 29, 2012
  • DOI: 10.1371/journal.pgen.1002603

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