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Research Article

Nos2 Inactivation Promotes the Development of Medulloblastoma in Ptch1+/− Mice by Deregulation of Gap43–Dependent Granule Cell Precursor Migration

  • Daniel Haag equal contributor,

    equal contributor Contributed equally to this work with: Daniel Haag, Petra Zipper

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Petra Zipper equal contributor,

    equal contributor Contributed equally to this work with: Daniel Haag, Petra Zipper

    Affiliation: Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany

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  • Viola Westrich,

    Affiliation: Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany

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  • Daniela Karra,

    Affiliation: Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany

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  • Karin Pfleger,

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Grischa Toedt,

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Frederik Blond,

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Nicolas Delhomme,

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Meinhard Hahn,

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Julia Reifenberger,

    Affiliation: Department of Dermatology, Heinrich Heine University, Düsseldorf, Germany

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  • Guido Reifenberger,

    Affiliation: Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany

    These authors were joint senior authors on this work.

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  • Peter Lichter mail

    Peter.Lichter@dkfz.de

    Affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Published: March 15, 2012
  • DOI: 10.1371/journal.pgen.1002572

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