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Research Article

A Downstream CpG Island Controls Transcript Initiation and Elongation and the Methylation State of the Imprinted Airn Macro ncRNA Promoter

  • Martha V. Koerner,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

    Current address: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

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  • Florian M. Pauler,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Quanah J. Hudson,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Federica Santoro,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Anna Sawicka,

    Affiliation: Max F. Perutz Laboratories, Department of Medical Biochemistry, Medical University of Vienna, Vienna, Austria

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  • Philipp M. Guenzl,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Stefan H. Stricker,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

    Current address: UCL Cancer Institute, University College London, London, United Kingdom

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  • Yvonne M. Schichl,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

    Current address: Department of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria

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  • Paulina A. Latos,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

    Current address: The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom

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  • Ruth M. Klement,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Katarzyna E. Warczok,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Jacek Wojciechowski,

    Affiliation: IMP/IMBA Transgenic Service, Research Institute of Molecular Pathology, Vienna, Austria

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  • Christian Seiser,

    Affiliation: Max F. Perutz Laboratories, Department of Medical Biochemistry, Medical University of Vienna, Vienna, Austria

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  • Robert Kralovics,

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Denise P. Barlow mail

    dbarlow@cemm.oeaw.ac.at

    Affiliation: CeMM–Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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  • Published: March 01, 2012
  • DOI: 10.1371/journal.pgen.1002540

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