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Research Article

The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity

  • Erin K. Butler equal contributor,

    equal contributor Contributed equally to this work with: Erin K. Butler, Aaron Voigt

    Affiliations: Department of Neurology, University Medical Center, RWTH Aachen, Aachen, Germany, Department of Neurodegeneration and Restorative Research, Center Molecular Physiology of the Brain (CMPB), Georg-August University Göttingen, Göttingen, Germany, Göttingen Graduate School for Neurosciences and Molecular Biology (GGNB), Göttingen, Germany

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  • Aaron Voigt equal contributor,

    equal contributor Contributed equally to this work with: Erin K. Butler, Aaron Voigt

    Affiliation: Department of Neurology, University Medical Center, RWTH Aachen, Aachen, Germany

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  • A. Kathrin Lutz,

    Affiliation: Neurobiochemistry, Adolf-Butenandt-Institute, Ludwig Maximilians University, Munich, Germany

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  • Jane P. Toegel,

    Affiliation: Department of Neurology, University Medical Center, RWTH Aachen, Aachen, Germany

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  • Ellen Gerhardt,

    Affiliation: Department of Neurodegeneration and Restorative Research, Center Molecular Physiology of the Brain (CMPB), Georg-August University Göttingen, Göttingen, Germany

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  • Peter Karsten,

    Affiliation: Department of Neurology, University Medical Center, RWTH Aachen, Aachen, Germany

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  • Björn Falkenburger,

    Affiliation: Department of Neurology, University Medical Center, RWTH Aachen, Aachen, Germany

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  • Andrea Reinartz,

    Affiliation: Department of Pathology, University Medical Center, RWTH Aachen, Aachen, Germany

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  • Konstanze F. Winklhofer,

    Affiliations: Neurobiochemistry, Adolf-Butenandt-Institute, Ludwig Maximilians University, Munich, Germany, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany

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  • Jörg B. Schulz mail

    jschulz@ukaachen.de

    Affiliations: Department of Neurology, University Medical Center, RWTH Aachen, Aachen, Germany, Jülich-Aachen Research Alliance (JARA) Brain, Jülich/Aachen, Germany

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  • Published: February 02, 2012
  • DOI: 10.1371/journal.pgen.1002488

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