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Research Article

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

  • Michael Blatzer equal contributor,

    equal contributor Contributed equally to this work with: Michael Blatzer, Bridget M. Barker

    Affiliation: Division of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria

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  • Bridget M. Barker equal contributor,

    equal contributor Contributed equally to this work with: Michael Blatzer, Bridget M. Barker

    Affiliation: Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America

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  • Sven D. Willger,

    Affiliation: Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America

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  • Nicola Beckmann,

    Affiliation: Division of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria

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  • Sara J. Blosser,

    Affiliation: Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America

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  • Elizabeth J. Cornish,

    Affiliation: Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America

    X
  • Aurelien Mazurie,

    Affiliation: Bioinformatics Core and Department of Microbiology, Montana State University, Bozeman, Montana, United States of America

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  • Nora Grahl,

    Affiliation: Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America

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  • Hubertus Haas mail,

    hubertus.haas@i-med.ac.at (HH); rcramer@montana.edu (RAC)

    Affiliation: Division of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria

    These authors also contributed equally to this work.

    X
  • Robert A. Cramer mail

    hubertus.haas@i-med.ac.at (HH); rcramer@montana.edu (RAC)

    Affiliation: Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America

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  • Published: December 01, 2011
  • DOI: 10.1371/journal.pgen.1002374

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