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Research Article

The NF1 Gene Contains Hotspots for L1 Endonuclease-Dependent De Novo Insertion

  • Katharina Wimmer mail,

    katharina.wimmer@i-med.ac.at (KW); lmessiaen@uab.edu (LM)

    Affiliation: Division Human Genetics, Medical University Innsbruck, Innsbruck, Austria

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  • Tom Callens,

    Affiliation: Medical Genomics Laboratory, Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Annekatrin Wernstedt,

    Affiliation: Division Human Genetics, Medical University Innsbruck, Innsbruck, Austria

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  • Ludwine Messiaen mail

    katharina.wimmer@i-med.ac.at (KW); lmessiaen@uab.edu (LM)

    Affiliation: Medical Genomics Laboratory, Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Published: November 17, 2011
  • DOI: 10.1371/journal.pgen.1002371

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