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Research Article

Cell Type–Specific Transcriptome Analysis Reveals a Major Role for Zeb1 and miR-200b in Mouse Inner Ear Morphogenesis

  • Ronna Hertzano mail,

    rhertzano@smail.umaryland.edu

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Ran Elkon,

    Affiliation: Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands

    X
  • Kiyoto Kurima,

    Affiliation: Molecular Biology and Genetics Section, Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America

    X
  • Annie Morrisson,

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Siaw-Lin Chan,

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Michelle Sallin,

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Andrew Biedlingmaier,

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Douglas S. Darling,

    Affiliation: Department of Oral Health and Rehabilitation and Center for Genetics and Molecular Medicine, University of Louisville, Louisville, Kentucky, United States of America

    X
  • Andrew J. Griffith,

    Affiliation: Molecular Biology and Genetics Section, Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America

    X
  • David J. Eisenman,

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Scott E. Strome

    Affiliation: Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Published: September 29, 2011
  • DOI: 10.1371/journal.pgen.1002309

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A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice

Kiyoto Kurima, Ronna Hertzano, Oksana Gavrilova, Kelly Monahan, Karl B. Shpargel, Garani Nadaraja, Yoshiyuki Kawashima, Kyu Yup Lee, Taku Ito, Yujiro Higashi, David J. Eisenman, ...
Research Article | published 29 Sep 2011 | PLOS Genetics
doi:10.1371/journal.pgen.1002307