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Research Article

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

  • Ayal Hendel equal contributor,

    equal contributor Contributed equally to this work with: Ayal Hendel, Peter H. L. Krijger

    Affiliation: Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

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  • Peter H. L. Krijger equal contributor,

    equal contributor Contributed equally to this work with: Ayal Hendel, Peter H. L. Krijger

    Affiliation: Division of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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  • Noam Diamant,

    Affiliation: Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

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  • Zohar Goren,

    Affiliation: Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

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  • Petra Langerak,

    Affiliation: Division of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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  • Jungmin Kim,

    Affiliation: Department of Radiation Oncology and Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Thomas Reißner,

    Affiliation: Department of Chemistry and Biochemistry, Ludwig Maximilians-University Munich, Munich, Germany

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  • Kyoo-young Lee,

    Affiliation: Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Nicholas E. Geacintov,

    Affiliation: Chemistry Department, New York University, New York, United States of America

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  • Thomas Carell,

    Affiliation: Department of Chemistry and Biochemistry, Ludwig Maximilians-University Munich, Munich, Germany

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  • Kyungjae Myung,

    Affiliation: Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Satoshi Tateishi,

    Affiliation: Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan

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  • Alan D'Andrea,

    Affiliation: Department of Radiation Oncology and Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Heinz Jacobs mail,

    zvi.livneh@weizmann.ac.il (ZL); h.jacobs@nki.nl (HJ)

    Affiliation: Division of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

    These authors also contributed equally to this work.

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  • Zvi Livneh mail

    zvi.livneh@weizmann.ac.il (ZL); h.jacobs@nki.nl (HJ)

    Affiliation: Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

    These authors also contributed equally to this work.

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  • Published: September 08, 2011
  • DOI: 10.1371/journal.pgen.1002262

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