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Research Article

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

  • Federico Innocenti equal contributor,

    equal contributor Contributed equally to this work with: Federico Innocenti, Gregory M. Cooper

    Affiliation: Cancer Research Center, Committee on Clinical Pharmacology and Pharmacogenomics, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Gregory M. Cooper equal contributor,

    equal contributor Contributed equally to this work with: Federico Innocenti, Gregory M. Cooper

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

    Current address: Hudson Alpha Institute, Huntsville, Alabama, United States of America

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  • Ian B. Stanaway,

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Eric R. Gamazon,

    Affiliation: Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Joshua D. Smith,

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Snezana Mirkov,

    Affiliation: Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Jacqueline Ramirez,

    Affiliation: Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Wanqing Liu,

    Affiliation: Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Yvonne S. Lin,

    Affiliations: Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington, United States of America, Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America

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  • Cliona Moloney,

    Affiliation: Merck Research Laboratories, Boston, Massachusetts, United States of America

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  • Shelly Force Aldred,

    Affiliation: SwitchGear Genomics, Menlo Park, California, United States of America

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  • Nathan D. Trinklein,

    Affiliation: SwitchGear Genomics, Menlo Park, California, United States of America

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  • Erin Schuetz,

    Affiliation: Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • Deborah A. Nickerson,

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Ken E. Thummel,

    Affiliations: Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington, United States of America, Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America

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  • Mark J. Rieder,

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Allan E. Rettie,

    Affiliation: Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington, United States of America

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  • Mark J. Ratain,

    Affiliation: Cancer Research Center, Committee on Clinical Pharmacology and Pharmacogenomics, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Nancy J. Cox,

    Affiliation: Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

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  • Christopher D. Brown mail

    caseybrown@uchicago.edu

    Affiliations: Institute for Genomics and Systems Biology, The University of Chicago and Argonne National Laboratory, Chicago, Illinois, United States of America, Departments of Human Genetics and Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America

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  • Published: May 26, 2011
  • DOI: 10.1371/journal.pgen.1002078

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