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Research Article

Genome Analysis Reveals Interplay between 5′UTR Introns and Nuclear mRNA Export for Secretory and Mitochondrial Genes

  • Can Cenik,

    Affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Hon Nian Chua,

    Affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Hui Zhang,

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Canada

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  • Stefan P. Tarnawsky,

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Canada

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  • Abdalla Akef,

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Canada

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  • Adnan Derti,

    Affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Murat Tasan,

    Affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Melissa J. Moore,

    Affiliation: Department of Biochemistry and Molecular Pharmacology, Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Alexander F. Palazzo mail,

    alex.palazzo@utoronto.ca (AFP); fritz_roth@hms.harvard.edu (FPR)

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Canada

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  • Frederick P. Roth mail

    alex.palazzo@utoronto.ca (AFP); fritz_roth@hms.harvard.edu (FPR)

    Affiliations: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Canada

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  • Published: April 14, 2011
  • DOI: 10.1371/journal.pgen.1001366

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