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Research Article

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

  • Ellen M. Wijsman mail,

    wijsman@u.washington.edu

    Affiliations: Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America, Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

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  • Nathan D. Pankratz,

    Affiliation: Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Yoonha Choi,

    Affiliation: Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

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  • Joseph H. Rothstein,

    Affiliation: Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America

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  • Kelley M. Faber,

    Affiliation: Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Rong Cheng,

    Affiliation: The Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

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  • Joseph H. Lee,

    Affiliation: The Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

    X
  • Thomas D. Bird,

    Affiliations: Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America, Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle Division, Seattle, Washington, United States of America, Department of Neurology, University of Washington, Seattle, Washington, United States of America

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  • David A. Bennett,

    Affiliation: Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America

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  • Ramon Diaz-Arrastia,

    Affiliation: Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Alison M. Goate,

    Affiliation: Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Martin Farlow,

    Affiliation: Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Bernardino Ghetti,

    Affiliation: Department of Pathology, Division of Neuropathology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Robert A. Sweet,

    Affiliation: Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Tatiana M. Foroud,

    Affiliation: Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Richard Mayeux,

    Affiliation: The Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

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  • The NIA-LOAD/NCRAD Family Study Group
  • Published: February 17, 2011
  • DOI: 10.1371/journal.pgen.1001308

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