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Research Article

Srf1 Is a Novel Regulator of Phospholipase D Activity and Is Essential to Buffer the Toxic Effects of C16:0 Platelet Activating Factor

  • Michael A. Kennedy,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Nazir Kabbani,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Jean-Philippe Lambert,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Leigh Anne Swayne,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Fida Ahmed,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Daniel Figeys,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Steffany A. L. Bennett,

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Jennnifer Bryan,

    Affiliation: Michael Smith Laboratories and Department of Statistics, University of British Columbia, Vancouver, Canada

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  • Kristin Baetz mail

    kbaetz@uottawa.ca

    Affiliation: Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

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  • Published: February 10, 2011
  • DOI: 10.1371/journal.pgen.1001299

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