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Research Article

Dynamic Switch of Negative Feedback Regulation in Drosophila Akt–TOR Signaling

  • Lutz Kockel mail,

    perrimon@receptor.med.harvard.edu (NP); lutz.kockel@ucsf.edu (LK)

    Affiliations: Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Diabetes Center, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Kimberly S. Kerr,

    Affiliation: Diabetes Center, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

    Current address: University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Michael Melnick,

    Affiliation: Cell Signaling Technology, Beverley, Massachusetts, United States of America

    Current address: CMEA Ventures, San Francisco, California, United States of America

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  • Katja Brückner,

    Affiliation: Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, California, United States of America

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  • Matthias Hebrok,

    Affiliation: Diabetes Center, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

    X
  • Norbert Perrimon mail

    perrimon@receptor.med.harvard.edu (NP); lutz.kockel@ucsf.edu (LK)

    Affiliation: Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: June 17, 2010
  • DOI: 10.1371/journal.pgen.1000990

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