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Research Article

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

  • J. Raphael Gibbs equal contributor,

    equal contributor Contributed equally to this work with: J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez

    Affiliations: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom

    X
  • Marcel P. van der Brug equal contributor,

    equal contributor Contributed equally to this work with: J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez

    Affiliations: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, Jupiter, Florida, United States of America

    X
  • Dena G. Hernandez equal contributor,

    equal contributor Contributed equally to this work with: J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez

    Affiliations: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom

    X
  • Bryan J. Traynor,

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Michael A. Nalls,

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Shiao-Lin Lai,

    Affiliations: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom

    X
  • Sampath Arepalli,

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Allissa Dillman,

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Ian P. Rafferty,

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Juan Troncoso,

    Affiliation: Division of Neuropathology, Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

    X
  • Robert Johnson,

    Affiliation: National Institute of Child Heath and Human Development Brain and Tissue Bank for Developmental Disorders, University of Maryland Medical School, Baltimore, Maryland, United States of America

    X
  • H. Ronald Zielke,

    Affiliation: National Institute of Child Heath and Human Development Brain and Tissue Bank for Developmental Disorders, University of Maryland Medical School, Baltimore, Maryland, United States of America

    X
  • Luigi Ferrucci,

    Affiliation: Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Dan L. Longo,

    Affiliation: Lymphocyte Cell Biology Unit, Laboratory of Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

    X
  • Mark R. Cookson mail,

    cookson@mail.nih.gov (MRC); singleta@mail.nih.gov (ABS)

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Andrew B. Singleton mail

    cookson@mail.nih.gov (MRC); singleta@mail.nih.gov (ABS)

    Affiliation: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: May 13, 2010
  • DOI: 10.1371/journal.pgen.1000952

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