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Research Article

KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading

  • Anna C. Groner,

    Affiliations: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Frontiers-in-Genetics National Center of Competence in Research, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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  • Sylvain Meylan,

    Affiliations: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Frontiers-in-Genetics National Center of Competence in Research, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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  • Angela Ciuffi,

    Affiliation: Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland

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  • Nadine Zangger,

    Affiliations: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Frontiers-in-Genetics National Center of Competence in Research, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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  • Giovanna Ambrosini,

    Affiliations: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

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  • Nicolas Dénervaud,

    Affiliation: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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  • Philipp Bucher,

    Affiliations: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

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  • Didier Trono mail

    didier.trono@epfl.ch

    Affiliations: School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Frontiers-in-Genetics National Center of Competence in Research, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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  • Published: March 05, 2010
  • DOI: 10.1371/journal.pgen.1000869

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