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Research Article

Progressive Purkinje Cell Degeneration in tambaleante Mutant Mice Is a Consequence of a Missense Mutation in HERC1 E3 Ubiquitin Ligase

  • Tomoji Mashimo equal contributor,

    equal contributor Contributed equally to this work with: Tomoji Mashimo, Ouadah Hadjebi

    Affiliations: Département de Biologie du Développement, Institut Pasteur, Paris, France, Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Ouadah Hadjebi equal contributor,

    equal contributor Contributed equally to this work with: Tomoji Mashimo, Ouadah Hadjebi

    Affiliation: Departament de Ciències Fisiològiques II, IDIBELL, Campus de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain

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  • Fabiola Amair-Pinedo,

    Affiliation: Departament de Ciències Fisiològiques II, IDIBELL, Campus de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain

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  • Toshiko Tsurumi,

    Affiliation: Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Francina Langa,

    Affiliation: Département de Biologie du Développement, Institut Pasteur, Paris, France

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  • Tadao Serikawa,

    Affiliation: Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Constantino Sotelo,

    Affiliation: Cátedra de Neurobiología del Desarrollo “Remedios Caro Almela”, Instituto de Neurociencias de Alicante, Universidad Miguel Hernández y CSIC, Alicante, Spain

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  • Jean-Louis Guénet mail,

    joseluisrosa@ub.edu (JLR);jlguenet@orange.fr (J-LG)

    Affiliation: Département de Biologie du Développement, Institut Pasteur, Paris, France

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  • Jose Luis Rosa mail

    joseluisrosa@ub.edu (JLR);jlguenet@orange.fr (J-LG)

    Affiliation: Departament de Ciències Fisiològiques II, IDIBELL, Campus de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain

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  • Published: December 24, 2009
  • DOI: 10.1371/journal.pgen.1000784

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