Advertisement
Research Article

Multi-Organ Expression Profiling Uncovers a Gene Module in Coronary Artery Disease Involving Transendothelial Migration of Leukocytes and LIM Domain Binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) Study

  • Sara Hägg equal contributor,

    equal contributor Contributed equally to this work with: Sara Hägg, Josefin Skogsberg, Jesper Lundström

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Josefin Skogsberg equal contributor,

    equal contributor Contributed equally to this work with: Sara Hägg, Josefin Skogsberg, Jesper Lundström

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Jesper Lundström equal contributor,

    equal contributor Contributed equally to this work with: Sara Hägg, Josefin Skogsberg, Jesper Lundström

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Peri Noori,

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Roland Nilsson,

    Affiliations: Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Hua Zhong,

    Affiliation: Rosetta Inpharmatics, Merck, Seattle, Washington, United States of America

    X
  • Shohreh Maleki,

    Affiliation: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    X
  • Ming-Mei Shang,

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Björn Brinne,

    Affiliation: Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden

    X
  • Maria Bradshaw,

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Vladimir B. Bajic,

    Affiliations: South African National Bioinformatics Institute (SANBI), University of the Western Cape, Cape Town, South Africa, Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia

    X
  • Ann Samnegård,

    Affiliation: Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden

    X
  • Angela Silveira,

    Affiliation: Cardiovascular Genetics Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    X
  • Lee M. Kaplan,

    Affiliation: Massachusetts General Hospital (MGH) Weight Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Bruna Gigante,

    Affiliation: Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    X
  • Karin Leander,

    Affiliation: Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    X
  • Ulf de Faire,

    Affiliation: Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    X
  • Stefan Rosfors,

    Affiliation: Department of Clinical Physiology, Stockholm Söder Hospital, Karolinska Institutet, Stockholm, Sweden

    X
  • Ulf Lockowandt,

    Affiliations: Department of Thoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

    X
  • Jan Liska,

    Affiliations: Department of Thoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

    X
  • Peter Konrad,

    Affiliation: Department of Surgery, Stockholm Söder Hospital, Karolinska Institutet, Stockholm, Sweden

    X
  • Rabbe Takolander,

    Affiliation: Department of Surgery, Stockholm Söder Hospital, Karolinska Institutet, Stockholm, Sweden

    X
  • Anders Franco-Cereceda,

    Affiliations: Department of Thoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

    X
  • Eric E. Schadt,

    Affiliation: Rosetta Inpharmatics, Merck, Seattle, Washington, United States of America

    X
  • Torbjörn Ivert,

    Affiliations: Department of Thoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

    X
  • Anders Hamsten,

    Affiliation: Cardiovascular Genetics Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    X
  • Jesper Tegnér,

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Johan Björkegren mail

    johan.bjorkegren@ki.se

    Affiliations: The Computational Medicine Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Computational Biology, Linköping Institute of Technology, Linköping University, Linköping, Sweden, Clinical Gene Networks AB, Karolinska Science Park, Stockholm, Sweden

    X
  • Published: December 04, 2009
  • DOI: 10.1371/journal.pgen.1000754

Media Coverage of this Article

Found additional news media or blog coverage for the article? Please let us know.