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Research Article

Functional Polymorphisms in PRODH Are Associated with Risk and Protection for Schizophrenia and Fronto-Striatal Structure and Function

  • Lucas Kempf,

    Affiliations: Unit of Systems Neuroscience in Psychiatry, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Kristin K. Nicodemus,

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

    Current address: Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

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  • Bhaskar Kolachana,

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Radhakrishna Vakkalanka,

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Beth A. Verchinski,

    Affiliations: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Neuroimaging Core Facility, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Michael F. Egan,

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

    Current address: Merck & Co, Inc., West Point, Pennsylvania, United States of America

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  • Richard E. Straub,

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Venkata A. Mattay,

    Affiliations: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Neuroimaging Core Facility, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Joseph H. Callicott,

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Daniel R. Weinberger mail,

    weinberd@mail.nih.gov (DRW); a.meyer-lindenberg@zi-mannheim.de (AML)

    Affiliation: Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Andreas Meyer-Lindenberg mail

    weinberd@mail.nih.gov (DRW); a.meyer-lindenberg@zi-mannheim.de (AML)

    Affiliations: Unit of Systems Neuroscience in Psychiatry, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Neuroimaging Core Facility, National Institute of Mental Health, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland, United States of America, Central Institute of Mental Health, Mannheim, Germany

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  • Published: November 07, 2008
  • DOI: 10.1371/journal.pgen.1000252

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