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Research Article

The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers

  • Shuji Kishi equal contributor mail,

    equal contributor Contributed equally to this work with: Shuji Kishi, Peter E. Bayliss

    shuji.kishi@schepens.harvard.edu (SK); thomas_roberts@dfci.harvard.edu (TMR)

    Affiliations: Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Peter E. Bayliss equal contributor,

    equal contributor Contributed equally to this work with: Shuji Kishi, Peter E. Bayliss

    Affiliations: Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Junzo Uchiyama,

    Affiliations: Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Eriko Koshimizu,

    Affiliations: Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America, Tokyo University of Marine Science and Technology, Tokyo, Japan

    X
  • Jie Qi,

    Affiliations: Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America, College of Marine Life Science, Ocean University of China, Qingdao, China

    X
  • Purushothama Nanjappa,

    Affiliations: Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Shintaro Imamura,

    Affiliations: Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Asiful Islam,

    Affiliations: Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Donna Neuberg,

    Affiliations: Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • Adam Amsterdam,

    Affiliation: Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • Thomas M. Roberts mail

    shuji.kishi@schepens.harvard.edu (SK); thomas_roberts@dfci.harvard.edu (TMR)

    Affiliations: Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: August 15, 2008
  • DOI: 10.1371/journal.pgen.1000152

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