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Research Article

Family-Based versus Unrelated Case-Control Designs for Genetic Associations

  • Evangelos Evangelou,

    Affiliation: Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece

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  • Thomas A Trikalinos,

    Affiliations: Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece, Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Georgia Salanti,

    Affiliation: Biostatistics Unit, Medical Research Council, Cambridge, United Kingdom

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  • John P. A Ioannidis mail

    To whom correspondence should be addressed. E-mail: jioannid@cc.uoi.gr

    Affiliations: Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece, Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece

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  • Published: August 11, 2006
  • DOI: 10.1371/journal.pgen.0020123

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