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Research Article

SLC26A4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc26a4 Mutant Mice

  • Xiangming Li,

    Affiliation: Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of America

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  • Joel D. Sanneman,

    Affiliation: Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of America

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  • Donald G. Harbidge,

    Affiliation: Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of America

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  • Fei Zhou,

    Affiliation: Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of America

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  • Taku Ito,

    Affiliation: Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America

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  • Raoul Nelson,

    Affiliation: Department of Pediatrics, Division of Nephrology, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America

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  • Nicolas Picard,

    Affiliation: Inserm, UMRS 970, Centre de recherche PARCC (Paris centre de recherche cardiovasculaire); Faculté de Médecine Paris Descartes, Sorbonne Paris Cité, Paris, France

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  • Régine Chambrey,

    Affiliation: Inserm, UMRS 970, Centre de recherche PARCC (Paris centre de recherche cardiovasculaire); Faculté de Médecine Paris Descartes, Sorbonne Paris Cité, Paris, France

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  • Dominique Eladari,

    Affiliations: Inserm, UMRS 970, Centre de recherche PARCC (Paris centre de recherche cardiovasculaire); Faculté de Médecine Paris Descartes, Sorbonne Paris Cité, Paris, France, Département de Physiologie, HEGP, AP-HP, Paris, France

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  • Tracy Miesner,

    Affiliation: Comparative Medicine Group, Kansas State University, Manhattan, Kansas, United States of America

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  • Andrew J. Griffith,

    Affiliation: Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America

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  • Daniel C. Marcus,

    Affiliation: Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of America

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  • Philine Wangemann mail

    wange@vet.ksu.edu

    Affiliation: Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of America

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  • Published: July 11, 2013
  • DOI: 10.1371/journal.pgen.1003641

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