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Research Article

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

  • Vinod Kumar,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Harm-Jan Westra equal contributor,

    equal contributor Contributed equally to this work with: Harm-Jan Westra, Juha Karjalainen, Daria V. Zhernakova

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Juha Karjalainen equal contributor,

    equal contributor Contributed equally to this work with: Harm-Jan Westra, Juha Karjalainen, Daria V. Zhernakova

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Daria V. Zhernakova equal contributor,

    equal contributor Contributed equally to this work with: Harm-Jan Westra, Juha Karjalainen, Daria V. Zhernakova

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Tõnu Esko,

    Affiliation: Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia

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  • Barbara Hrdlickova,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Rodrigo Almeida,

    Affiliations: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Graduate Program in Health Sciences, University of Brasilia School of Health Sciences, Brasilia, Brazil

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  • Alexandra Zhernakova,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Eva Reinmaa,

    Affiliation: Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia

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  • Urmo Võsa,

    Affiliation: Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia

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  • Marten H. Hofker,

    Affiliation: Molecular Genetics Section, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Rudolf S. N. Fehrmann,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Jingyuan Fu,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Sebo Withoff,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Andres Metspalu,

    Affiliation: Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia

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  • Lude Franke ,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

    These authors were joint senior authors on this work.

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  • Cisca Wijmenga mail

    c.wijmenga@umcg.nl

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

    These authors were joint senior authors on this work.

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  • Published: January 17, 2013
  • DOI: 10.1371/journal.pgen.1003201

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