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Research Article

Genes Contributing to Pain Sensitivity in the Normal Population: An Exome Sequencing Study

  • Frances M. K. Williams,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

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  • Serena Scollen,

    Affiliation: Pfizer Limited, Neusentis, Granta Park, Cambridge, United Kingdom

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  • Dandan Cao,

    Affiliation: BGI–Shenzhen, Shenzhen, China

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  • Yasin Memari,

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

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  • Craig L. Hyde,

    Affiliation: Pfizer Research Laboratories, Groton, Connecticut, United States of America

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  • Baohong Zhang,

    Affiliation: Pfizer Research Laboratories, Groton, Connecticut, United States of America

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  • Benjamin Sidders,

    Affiliation: Pfizer Limited, Neusentis, Granta Park, Cambridge, United Kingdom

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  • Daniel Ziemek,

    Affiliation: Worldwide R&D, Pfizer, Cambridge, Massachusetts, United States of America

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  • Yujian Shi,

    Affiliation: BGI–Shenzhen, Shenzhen, China

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  • Juliette Harris,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

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  • Ian Harrow,

    Affiliation: Pfizer Global Research and Development, Sandwich, United Kingdom

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  • Brian Dougherty,

    Affiliation: Pfizer Research Laboratories, Groton, Connecticut, United States of America

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  • Anders Malarstig,

    Affiliation: Pfizer Limited, Neusentis, Granta Park, Cambridge, United Kingdom

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  • Robert McEwen,

    Affiliation: Pfizer Global Research and Development, Sandwich, United Kingdom

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  • Joel C. Stephens,

    Affiliation: Pfizer Research Laboratories, Groton, Connecticut, United States of America

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  • Ketan Patel,

    Affiliation: Pfizer Global Research and Development, Sandwich, United Kingdom

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  • Cristina Menni,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

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  • So-Youn Shin,

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

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  • Dylan Hodgkiss,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

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  • Gabriela Surdulescu,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

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  • Wen He,

    Affiliation: Pfizer Research Laboratories, Groton, Connecticut, United States of America

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  • Xin Jin,

    Affiliations: BGI–Shenzhen, Shenzhen, China, School of Bioscience and Biotechnology, South China University of Technology, Guangzhou, China

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  • Stephen B. McMahon,

    Affiliation: Wolfson CARD, King's College London, London, United Kingdom

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  • Nicole Soranzo equal contributor,

    equal contributor Contributed equally to this work with: Nicole Soranzo, Sally John, Jun Wang, Tim D. Spector

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

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  • Sally John equal contributor,

    equal contributor Contributed equally to this work with: Nicole Soranzo, Sally John, Jun Wang, Tim D. Spector

    Affiliation: Pfizer Research Laboratories, Groton, Connecticut, United States of America

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  • Jun Wang equal contributor mail,

    equal contributor Contributed equally to this work with: Nicole Soranzo, Sally John, Jun Wang, Tim D. Spector

    wangjun30@gmail.com (JW); tim.spector@kcl.ac.uk (TDS)

    Affiliations: BGI–Shenzhen, Shenzhen, China, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark, Department of Biology, University of Copenhagen, Copenhagen, Denmark

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  • Tim D. Spector equal contributor mail

    equal contributor Contributed equally to this work with: Nicole Soranzo, Sally John, Jun Wang, Tim D. Spector

    wangjun30@gmail.com (JW); tim.spector@kcl.ac.uk (TDS)

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

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  • Published: December 20, 2012
  • DOI: 10.1371/journal.pgen.1003095

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