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Research Article

Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

  • Fanggeng Zou equal contributor,

    equal contributor Contributed equally to this work with: Fanggeng Zou, High Seng Chai, Curtis S. Younkin, Mariet Allen

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • High Seng Chai equal contributor,

    equal contributor Contributed equally to this work with: Fanggeng Zou, High Seng Chai, Curtis S. Younkin, Mariet Allen

    Affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Curtis S. Younkin equal contributor,

    equal contributor Contributed equally to this work with: Fanggeng Zou, High Seng Chai, Curtis S. Younkin, Mariet Allen

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Mariet Allen equal contributor,

    equal contributor Contributed equally to this work with: Fanggeng Zou, High Seng Chai, Curtis S. Younkin, Mariet Allen

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Julia Crook,

    Affiliation: Department of Biostatistics, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • V. Shane Pankratz,

    Affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Minerva M. Carrasquillo,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Christopher N. Rowley,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Asha A. Nair,

    Affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Sumit Middha,

    Affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Sooraj Maharjan,

    Affiliation: Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Thuy Nguyen,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Li Ma,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Kimberly G. Malphrus,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

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  • Ryan Palusak,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Sarah Lincoln,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Gina Bisceglio,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Constantin Georgescu,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Naomi Kouri,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Christopher P. Kolbert,

    Affiliation: Microarray Core, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Jin Jen,

    Affiliation: Microarray Core, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Jonathan L. Haines,

    Affiliation: Department of Molecular Physiology and Biophysics and Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America

    X
  • Richard Mayeux,

    Affiliation: Gertrude H. Sergievsky Center, Department of Neurology, and Taub Institute on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, United States of America

    X
  • Margaret A. Pericak-Vance,

    Affiliation: The John P. Hussman Institute for Human Genomics and Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America

    X
  • Lindsay A. Farrer,

    Affiliation: Departments of Biostatistics, Medicine (Genetics Program), Ophthalmology, Neurology, and Epidemiology, Boston University, Boston, Massachusetts, United States of America

    X
  • Gerard D. Schellenberg,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Alzheimer's Disease Genetics Consortium,

    Membership of the Alzheimer's Disease Genetics Consortium (ADGC) is provided in the Acknowledgments.

    X
  • Ronald C. Petersen,

    Affiliation: Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Neill R. Graff-Radford,

    Affiliation: Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Dennis W. Dickson,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Steven G. Younkin,

    Affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Nilüfer Ertekin-Taner mail

    taner.nilufer@mayo.edu

    Affiliations: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America, Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America

    X
  • Published: June 07, 2012
  • DOI: 10.1371/journal.pgen.1002707

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