Advertisement
Research Article

Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma

  • Leonieke M. E. van Koolwijk equal contributor,

    equal contributor Contributed equally to this work with: Leonieke M. E. van Koolwijk, Wishal D. Ramdas

    Affiliations: Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands, Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Wishal D. Ramdas equal contributor,

    equal contributor Contributed equally to this work with: Leonieke M. E. van Koolwijk, Wishal D. Ramdas

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • M. Kamran Ikram,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Neurology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Nomdo M. Jansonius,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

    X
  • Francesca Pasutto,

    Affiliation: Institute of Human Genetics, University Erlangen-Nuremberg, Erlangen, Germany

    X
  • Pirro G. Hysi,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

    X
  • Stuart Macgregor,

    Affiliation: Queensland Institute of Medical Research, Brisbane, Australia

    X
  • Sarah F. Janssen,

    Affiliation: Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands

    X
  • Alex W. Hewitt,

    Affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia

    X
  • Ananth C. Viswanathan,

    Affiliation: NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom

    X
  • Jacoline B. ten Brink,

    Affiliation: Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands

    X
  • S. Mohsen Hosseini,

    Affiliation: Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada

    X
  • Najaf Amin,

    Affiliation: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Dominiek D. G. Despriet,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Jacqueline J. M. Willemse-Assink,

    Affiliation: Department of Ophthalmology, Amphia Hospital, Breda, The Netherlands

    X
  • Rogier Kramer,

    Affiliation: Department of Ophthalmology, Franciscus Hospital, Roosendaal, The Netherlands

    X
  • Fernando Rivadeneira,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Internal Medicine, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Maksim Struchalin,

    Affiliation: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Yurii S. Aulchenko,

    Affiliation: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Nicole Weisschuh,

    Affiliation: Molecular Genetics Laboratory, University Eye Hospital, Tübingen, Germany

    X
  • Matthias Zenkel,

    Affiliation: Department of Ophthalmology, University of Erlangen-Nuremberg, Erlangen, Germany

    X
  • Christian Y. Mardin,

    Affiliation: Department of Ophthalmology, University of Erlangen-Nuremberg, Erlangen, Germany

    X
  • Eugen Gramer,

    Affiliation: University Eye Hospital, Würzburg, Germany

    X
  • Ulrich Welge-Lüssen,

    Affiliation: Department of Ophthalmology, Friedrich-Alexander University, Erlangen, Germany

    X
  • Grant W. Montgomery,

    Affiliation: Queensland Institute of Medical Research, Brisbane, Australia

    X
  • Francis Carbonaro,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

    X
  • Terri L. Young,

    Affiliation: Center for Human Genetics, Duke University, Durham, North Carolina, United States of America

    X
  • The DCCT/EDIC Research Group,
  • Céline Bellenguez,

    Affiliation: Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

    X
  • Peter McGuffin,

    Affiliation: MRC Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College, London, United Kingdom

    X
  • Paul J. Foster,

    Affiliation: NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom

    X
  • Fotis Topouzis,

    Affiliation: Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece

    X
  • Paul Mitchell,

    Affiliation: Centre for Vision Research, University of Sydney, Sydney, Australia

    X
  • Jie Jin Wang,

    Affiliation: Centre for Vision Research, University of Sydney, Sydney, Australia

    X
  • Tien Y. Wong,

    Affiliations: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia, Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    X
  • Monika A. Czudowska,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Albert Hofman,

    Affiliation: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Andre G. Uitterlinden,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Internal Medicine, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Roger C. W. Wolfs,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Paulus T. V. M. de Jong,

    Affiliations: Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands, Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands

    X
  • Ben A. Oostra,

    Affiliation: Department of Clinical Genetics, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Andrew D. Paterson,

    Affiliations: Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

    X
  • Wellcome Trust Case Control Consortium 2,

    Membership of WTCCC2 is provided in the Acknowledgments.

    X
  • David A. Mackey,

    Affiliation: Lions Eye Institute, University of Western Australia, Centre for Ophthalmology and Visual Science, Perth, Australia

    X
  • Arthur A. B. Bergen,

    Affiliations: Department of Molecular Ophthalmogenetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands, Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands, Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands

    X
  • André Reis,

    Affiliation: Institute of Human Genetics, University Erlangen-Nuremberg, Erlangen, Germany

    X
  • Christopher J. Hammond,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

    X
  • Johannes R. Vingerling,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Hans G. Lemij,

    Affiliation: Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands

    X
  • Caroline C. W. Klaver,

    Affiliations: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Cornelia M. van Duijn mail

    c.vanduijn@erasmusmc.nl

    Affiliation: Department of Epidemiology, The Erasmus University Medical Center, Rotterdam, The Netherlands

    X
  • Published: May 03, 2012
  • DOI: 10.1371/journal.pgen.1002611

Viewed info

Cited info

Saved info

Discussed info

Questions or concerns about usage data? Please let us know.