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Research Article

Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages

  • Maggie L. Chow equal contributor,

    equal contributor Contributed equally to this work with: Maggie L. Chow, Tiziano Pramparo

    Affiliation: Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Tiziano Pramparo equal contributor,

    equal contributor Contributed equally to this work with: Maggie L. Chow, Tiziano Pramparo

    Affiliations: Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America, Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Mary E. Winn,

    Affiliations: Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America, Graduate Program in Biomedical Sciences, Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Cynthia Carter Barnes,

    Affiliation: Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Hai-Ri Li,

    Affiliation: Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Lauren Weiss,

    Affiliation: Department of Psychiatry, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Jian-Bing Fan,

    Affiliation: Illumina, San Diego, California, United States of America

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  • Sarah Murray,

    Affiliation: Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America

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  • Craig April,

    Affiliation: Illumina, San Diego, California, United States of America

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  • Haim Belinson,

    Affiliation: Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Xiang-Dong Fu ,

    Affiliation: Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

    These authors were joint senior authors on this work.

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  • Anthony Wynshaw-Boris ,

    Affiliation: Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

    These authors were joint senior authors on this work.

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  • Nicholas J. Schork mail,

    nschork@scripps.edu (NJS); ecourchesne@ucsd.edu (EC)

    Affiliation: Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America

    These authors were joint senior authors on this work.

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  • Eric Courchesne mail

    nschork@scripps.edu (NJS); ecourchesne@ucsd.edu (EC)

    Affiliation: Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

    These authors were joint senior authors on this work.

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  • Published: March 22, 2012
  • DOI: 10.1371/journal.pgen.1002592

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