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Research Article

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD

  • Carsten A. Böger,

    Affiliation: Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany

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  • Mathias Gorski,

    Affiliations: Department of Epidemiology and Preventive Medicine, University Hospital Regensburg, Regensburg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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  • Man Li,

    Affiliation: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Michael M. Hoffmann,

    Affiliation: Clinical Chemistry, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany

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  • Chunmei Huang,

    Affiliation: Division of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Qiong Yang,

    Affiliation: Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

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  • Alexander Teumer,

    Affiliation: Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany

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  • Vera Krane,

    Affiliation: University of Würzburg, Department of Medicine 1, Division of Nephrology, University Hospital Würzburg, Würzburg, Germany

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  • Conall M. O'Seaghdha,

    Affiliations: Division of Nephrology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, NHLBI's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts, United States of America

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  • Zoltán Kutalik,

    Affiliations: Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

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  • H.-Erich Wichmann,

    Affiliations: Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany, Klinikum Großhadern, Munich, Germany

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  • Thomas Haak,

    Affiliation: Diabetes Klinik Bad Mergentheim, Bad Mergentheim, Germany

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  • Eva Boes,

    Affiliation: Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

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  • Stefan Coassin,

    Affiliation: Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

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  • Josef Coresh,

    Affiliation: Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Barbara Kollerits,

    Affiliation: Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

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  • Margot Haun,

    Affiliation: Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

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  • Bernhard Paulweber,

    Affiliation: First Department of Internal Medicine, Paracelsus Medical University, Salzburg, Austria

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  • Anna Köttgen,

    Affiliations: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Renal Division, University Hospital of Freiburg, Freiburg, Germany

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  • Guo Li,

    Affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America

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  • Michael G. Shlipak,

    Affiliations: Division of General Internal Medicine, San Francisco VA Medical Center, San Francisco, California, United States of America, Department of Medicine, Epidemiology, and Biostatistics, University of California San Francisco, San Francisco, California, United States of America

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  • Neil Powe,

    Affiliation: Department of Medicine, San Francisco General Hospital and University of California San Francisco, San Francisco, California, United States of America

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  • Shih-Jen Hwang,

    Affiliation: NHLBI's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts, United States of America

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  • Abbas Dehghan,

    Affiliations: Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands

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  • Fernando Rivadeneira,

    Affiliations: Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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  • André Uitterlinden,

    Affiliations: Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Albert Hofman,

    Affiliations: Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands

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  • Jacques S. Beckmann,

    Affiliation: Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

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  • Bernhard K. Krämer,

    Affiliation: University Medical Centre Mannheim, 5th Department of Medicine, Mannheim, Germany

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  • Jacqueline Witteman,

    Affiliations: Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands

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  • Murielle Bochud,

    Affiliation: University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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  • David Siscovick,

    Affiliation: Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle, Washington, United States of America

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  • Rainer Rettig,

    Affiliation: Institute of Physiology, University of Greifswald, Greifswald, Germany

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  • Florian Kronenberg,

    Affiliation: Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

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  • Christoph Wanner,

    Affiliation: University of Würzburg, Department of Medicine 1, Division of Nephrology, University Hospital Würzburg, Würzburg, Germany

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  • Ravi I. Thadhani,

    Affiliation: Division of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Iris M. Heid,

    Affiliations: Department of Epidemiology and Preventive Medicine, University Hospital Regensburg, Regensburg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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  • Caroline S. Fox equal contributor mail,

    equal contributor Contributed equally to this work with: Caroline S. Fox, W. H. Kao

    foxca@nhlbi.nih.gov (CSF); wkao@jhsph.edu (WHK)

    Affiliations: NHLBI's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts, United States of America, Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • W. H. Kao equal contributor mail,

    equal contributor Contributed equally to this work with: Caroline S. Fox, W. H. Kao

    foxca@nhlbi.nih.gov (CSF); wkao@jhsph.edu (WHK)

    Affiliation: Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • The CKDGen Consortium
  • Published: September 29, 2011
  • DOI: 10.1371/journal.pgen.1002292

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