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Research Article

The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO

  • Gizem Rizki,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Terri Naoko Iwata,

    Affiliation: Department of Molecular Biology and Genetics, Field of Comparative Biomedical Sciences, Cornell University, Ithaca, New York, United States of America

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  • Ji Li,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Christian G. Riedel,

    Affiliation: Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Simches Research Center, Boston, Massachusetts, United States of America

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  • Colette Lafontaine Picard,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Max Jan,

    Affiliation: Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Coleen T. Murphy,

    Affiliation: Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Siu Sylvia Lee mail

    sylvia.lee@cornell.edu

    Affiliations: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America, Department of Molecular Biology and Genetics, Field of Comparative Biomedical Sciences, Cornell University, Ithaca, New York, United States of America

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  • Published: September 01, 2011
  • DOI: 10.1371/journal.pgen.1002235

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