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Research Article

Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

  • Sharon A. Chung mail,

    sharon.chung@ucsf.edu (SAC); lindsey.criswell@ucsf.edu (LAC)

    Affiliation: Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Kimberly E. Taylor,

    Affiliation: Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Robert R. Graham,

    Affiliation: ITGR Human Genetics, Genentech, South San Francisco, California, United States of America

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  • Joanne Nititham,

    Affiliation: Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Annette T. Lee,

    Affiliation: Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, New York, United States of America

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  • Ward A. Ortmann,

    Affiliation: ITGR Human Genetics, Genentech, South San Francisco, California, United States of America

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  • Chaim O. Jacob,

    Affiliation: Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Marta E. Alarcón-Riquelme,

    Affiliations: Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden, Andalusian Center for Genomics and Oncological Research, Pfizer-University of Granada-Junta de Andalucía, Granada, Spain, Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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  • Betty P. Tsao,

    Affiliation: Department of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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  • John B. Harley,

    Affiliation: US Department of Veterans Affairs Medical Center and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

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  • Patrick M. Gaffney,

    Affiliation: Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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  • Kathy L. Moser,

    Affiliation: Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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  • SLEGEN,

    For membership of The International Consortium on the Genetics of Systemic Lupus Erythematosus please see the Acknowledgments.

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  • Michelle Petri,

    Affiliation: Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • F. Yesim Demirci,

    Affiliation: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • M. Ilyas Kamboh,

    Affiliation: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Susan Manzi,

    Affiliation: Allegheny-Singer Research Institute, Pittsburgh, Pennsylvania, United States of America

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  • Peter K. Gregersen,

    Affiliation: Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, New York, United States of America

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  • Carl D. Langefeld,

    Affiliation: Department of Biostatistical Sciences, Wake Forest University Health Sciences, Wake Forest, North Carolina, United States of America

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  • Timothy W. Behrens,

    Affiliation: ITGR Human Genetics, Genentech, South San Francisco, California, United States of America

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  • Lindsey A. Criswell mail

    sharon.chung@ucsf.edu (SAC); lindsey.criswell@ucsf.edu (LAC)

    Affiliation: Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Published: March 03, 2011
  • DOI: 10.1371/journal.pgen.1001323

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