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Research Article

Mutations in Zebrafish lrp2 Result in Adult-Onset Ocular Pathogenesis That Models Myopia and Other Risk Factors for Glaucoma

  • Kerry N. Veth,

    Affiliation: Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Jason R. Willer,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky, United States of America

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  • Ross F. Collery,

    Affiliation: Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Matthew P. Gray,

    Affiliation: Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Gregory B. Willer,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky, United States of America

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  • Daniel S. Wagner,

    Affiliation: Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

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  • Mary C. Mullins,

    Affiliation: Department of Cell and Developmental Biology, University of Pennsylvania Medical School, Philadelphia, Pennsylvania, United States of America

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  • Ava J. Udvadia,

    Affiliation: Department of Biological Sciences, University of Wisconsin–Milwaukee, Milwaukee, Wisconsin, United States of America

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  • Richard S. Smith,

    Affiliation: Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America

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  • Simon W. M. John,

    Affiliation: Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America

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  • Ronald G. Gregg,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky, United States of America

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  • Brian A. Link mail

    blink@mcw.edu

    Affiliation: Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Published: February 17, 2011
  • DOI: 10.1371/journal.pgen.1001310

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