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Research Article

Identification of a Functional Genetic Variant at 16q12.1 for Breast Cancer Risk: Results from the Asia Breast Cancer Consortium

  • Jirong Long,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Qiuyin Cai,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Xiao-Ou Shu,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Shimian Qu,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Chun Li,

    Affiliation: Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Ying Zheng,

    Affiliation: Shanghai Center for Disease Control and Prevention, Shanghai, China

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  • Kai Gu,

    Affiliation: Shanghai Center for Disease Control and Prevention, Shanghai, China

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  • Wenjing Wang,

    Affiliation: Shanghai Center for Disease Control and Prevention, Shanghai, China

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  • Yong-Bing Xiang,

    Affiliation: Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China

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  • Jiarong Cheng,

    Affiliation: Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China

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  • Kexin Chen,

    Affiliation: Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

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  • Lina Zhang,

    Affiliation: Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

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  • Hong Zheng,

    Affiliation: Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

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  • Chen-Yang Shen,

    Affiliation: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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  • Chiun-Sheng Huang,

    Affiliation: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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  • Ming-Feng Hou,

    Affiliation: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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  • Hongbing Shen,

    Affiliation: Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing, China

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  • Zhibin Hu,

    Affiliation: Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing, China

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  • Furu Wang,

    Affiliation: Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing, China

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  • Sandra L. Deming,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Mark C. Kelley,

    Affiliation: Division of Surgical Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Martha J. Shrubsole,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Ui Soon Khoo,

    Affiliation: Department of Pathology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China

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  • Kelvin Y. K. Chan,

    Affiliation: Division of Surgical Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Sum Yin Chan,

    Affiliation: Department of Pathology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China

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  • Christopher A. Haiman,

    Affiliation: Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America

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  • Brian E. Henderson,

    Affiliation: Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America

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  • Loic Le Marchand,

    Affiliation: Epidemiology Program, Cancer Research Center, University of Hawaii, Honolulu, Hawaii, United States of America

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  • Motoki Iwasaki,

    Affiliation: Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan

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  • Yoshio Kasuga,

    Affiliation: Department of Surgery, Nagano Matsushiro General Hospital, Nagano, Japan

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  • Shoichiro Tsugane,

    Affiliation: Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan

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  • Keitaro Matsuo,

    Affiliation: Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan

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  • Kazuo Tajima,

    Affiliation: Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan

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  • Hiroji Iwata,

    Affiliation: Department of Breast Oncology, Aichi Cancer Center Central Hospital, Nagoya, Japan

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  • Bo Huang,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Jiajun Shi,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Guoliang Li,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Wanqing Wen,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Yu-Tang Gao,

    Affiliation: Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China

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  • Wei Lu,

    Affiliation: Shanghai Center for Disease Control and Prevention, Shanghai, China

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  • Wei Zheng mail

    wei.zheng@vanderbilt.edu

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: June 24, 2010
  • DOI: 10.1371/journal.pgen.1001002

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