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Research Article

A Mouse Model of the Human Fragile X Syndrome I304N Mutation

  • Julie B. Zang,

    Affiliation: Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America

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  • Elena D. Nosyreva,

    Affiliation: Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Corinne M. Spencer,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Lenora J. Volk,

    Affiliation: Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Kiran Musunuru,

    Affiliation: Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America

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  • Ru Zhong,

    Affiliation: Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America

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  • Elizabeth F. Stone,

    Affiliation: Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America

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  • Lisa A. Yuva-Paylor,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Kimberly M. Huber,

    Affiliation: Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Richard Paylor,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Jennifer C. Darnell mail,

    darneje@rockefeller.edu

    Affiliation: Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America

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  • Robert B. Darnell

    Affiliations: Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

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  • Published: December 11, 2009
  • DOI: 10.1371/journal.pgen.1000758

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