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Research Article

A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis

  • Claudia Gaspar,

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Patrick Franken,

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Lia Molenaar,

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Cor Breukel,

    Affiliation: Human and Clinical Genetics Center, LUMC, Leiden, The Netherlands

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  • Martin van der Valk,

    Affiliation: Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands

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  • Ron Smits,

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Riccardo Fodde mail

    r.fodde@erasmusmc.nl

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Published: July 03, 2009
  • DOI: 10.1371/journal.pgen.1000547

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