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Research Article

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

  • Elke Ericson,

    Affiliations: Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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  • Marinella Gebbia,

    Affiliations: Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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  • Lawrence E. Heisler,

    Affiliations: Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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  • Jan Wildenhain,

    Affiliation: School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Mike Tyers,

    Affiliations: Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Guri Giaever,

    Affiliations: Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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  • Corey Nislow mail

    corey.nislow@utoronto.ca

    Affiliations: Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada

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  • Published: August 08, 2008
  • DOI: 10.1371/journal.pgen.1000151

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