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Research Article

Unintentional miRNA Ablation Is a Risk Factor in Gene Knockout Studies: A Short Report

  • Ivan Osokine,

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco (UCSF) Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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  • Ruby Hsu,

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco (UCSF) Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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  • Gabriel B Loeb,

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco (UCSF) Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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  • Michael T McManus mail

    To whom correspondence should be addressed. E-mail: michael.mcmanus@ucsf.edu

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco (UCSF) Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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  • Published: February 15, 2008
  • DOI: 10.1371/journal.pgen.0040034

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