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Research Article

Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination

  • Ionel Sandovici,

    Affiliation: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

    ¤a Current address: Laboratory of Developmental Genetics and Imprinting, Developmental Genetics Programme, The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom

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  • Sacha Kassovska-Bratinova,

    Affiliation: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Joe E Vaughan,

    Affiliation: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

    ¤b Current address: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Rae Stewart,

    Affiliation: College of Science and Technology, Temple University, Philadelphia, Pennsylvania, United States of America

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  • Mark Leppert,

    Affiliation: Eccles Institute of Human Genetics, and Department of Human Genetics, University of Utah, Salt Lake City, Utah, United States of America

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  • Carmen Sapienza mail

    To whom correspondence should be addressed. E-mail: sapienza@temple.edu

    Affiliations: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Published: July 07, 2006
  • DOI: 10.1371/journal.pgen.0020101

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