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Research Article

Age-Dependent Transition from Cell-Level to Population-Level Control in Murine Intestinal Homeostasis Revealed by Coalescence Analysis

  • Zheng Hu,

    Affiliations: Center for Computational Biology and Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, Graduate University of Chinese Academy of Sciences, Beijing, China

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  • Yun-Xin Fu,

    Affiliation: Human Genetics Center and Division of Biostatistics, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Anthony J. Greenberg,

    Affiliation: Departments of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

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  • Chung-I Wu mail,

    weiweizhai@big.ac.cn (WZ); ciwu@uchicago.edu (C-IW)

    Affiliations: Center for Computational Biology and Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, United States of America

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  • Weiwei Zhai mail

    weiweizhai@big.ac.cn (WZ); ciwu@uchicago.edu (C-IW)

    Affiliations: Center for Computational Biology and Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, National Center for Mathematics and Interdisciplinary Sciences, Chinese Academy of Sciences, Beijing, China

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  • Published: February 28, 2013
  • DOI: 10.1371/journal.pgen.1003326

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