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Research Article

Phosphatase-Dead Myotubularin Ameliorates X-Linked Centronuclear Myopathy Phenotypes in Mice

  • Leonela Amoasii equal contributor,

    equal contributor Contributed equally to this work with: Leonela Amoasii, Dimitri L. Bertazzi

    Affiliation: Department of Translational Medecine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, Illkirch, France

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  • Dimitri L. Bertazzi equal contributor,

    equal contributor Contributed equally to this work with: Leonela Amoasii, Dimitri L. Bertazzi

    Affiliation: Department of Molecular and Cellular Genetics, UMR7156, Université de Strasbourg and CNRS, Strasbourg, France

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  • Hélène Tronchère,

    Affiliation: INSERM, U1048 and Université Toulouse 3, I2MC, Toulouse, France

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  • Karim Hnia,

    Affiliation: Department of Translational Medecine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, Illkirch, France

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  • Gaëtan Chicanne,

    Affiliation: INSERM, U1048 and Université Toulouse 3, I2MC, Toulouse, France

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  • Bruno Rinaldi,

    Affiliation: Department of Molecular and Cellular Genetics, UMR7156, Université de Strasbourg and CNRS, Strasbourg, France

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  • Belinda S. Cowling,

    Affiliation: Department of Translational Medecine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, Illkirch, France

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  • Arnaud Ferry,

    Affiliation: UMRS974, Université Pierre et Marie Curie, Paris, France

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  • Bruno Klaholz,

    Affiliation: Department of Integrated Structural Biology, IGBMC, INSERM U964, CNRS UMR7104, Université de Strasbourg, Illkirch, France

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  • Bernard Payrastre mail,

    S.Friant@unistra.fr (SF); jocelyn@igbmc.fr (JL); bernard.payrastre@inserm.fr (BP)

    Affiliations: INSERM, U1048 and Université Toulouse 3, I2MC, Toulouse, France, CHU de Toulouse, Laboratoire d'Hématologie, Toulouse, France

    These authors were joint senior authors on this work.

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  • Jocelyn Laporte mail,

    S.Friant@unistra.fr (SF); jocelyn@igbmc.fr (JL); bernard.payrastre@inserm.fr (BP)

    Affiliation: Department of Translational Medecine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, Illkirch, France

    These authors were joint senior authors on this work.

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  • Sylvie Friant mail

    S.Friant@unistra.fr (SF); jocelyn@igbmc.fr (JL); bernard.payrastre@inserm.fr (BP)

    Affiliation: Department of Molecular and Cellular Genetics, UMR7156, Université de Strasbourg and CNRS, Strasbourg, France

    These authors were joint senior authors on this work.

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  • Published: October 11, 2012
  • DOI: 10.1371/journal.pgen.1002965

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