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Research Article

Physiological Notch Signaling Maintains Bone Homeostasis via RBPjk and Hey Upstream of NFATc1

  • Xiaolin Tu,

    Affiliation: Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

    Current address: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Jianquan Chen,

    Affiliation: Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Joohyun Lim,

    Affiliation: Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Courtney M. Karner,

    Affiliation: Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Seung-Yon Lee,

    Affiliation: Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Julia Heisig,

    Affiliation: Developmental Biochemistry, Biocentre, University of Wuerzburg, Wuerzburg, Germany

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  • Cornelia Wiese,

    Affiliation: Developmental Biochemistry, Biocentre, University of Wuerzburg, Wuerzburg, Germany

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  • Kameswaran Surendran,

    Affiliation: Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Raphael Kopan,

    Affiliation: Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Manfred Gessler,

    Affiliation: Developmental Biochemistry, Biocentre, University of Wuerzburg, Wuerzburg, Germany

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  • Fanxin Long mail

    flong@wustl.edu

    Affiliations: Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Published: March 22, 2012
  • DOI: 10.1371/journal.pgen.1002577

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