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Research Article

Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria

  • Song Liu equal contributor,

    equal contributor Contributed equally to this work with: Song Liu, Tomoyo Sawada

    Affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Tomoyo Sawada equal contributor,

    equal contributor Contributed equally to this work with: Song Liu, Tomoyo Sawada

    Affiliations: Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan

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  • Seongsoo Lee,

    Affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Wendou Yu,

    Affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • George Silverio,

    Affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Philomena Alapatt,

    Affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Ivan Millan,

    Affiliation: Neuroscience Program, Stanford University School of Medicine, Stanford, California, United States of America

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  • Alice Shen,

    Affiliation: College of Arts and Sciences, Washington University, St. Louis, Missouri, United States of America

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  • William Saxton,

    Affiliation: Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Tomoko Kanao,

    Affiliation: Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan

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  • Ryosuke Takahashi,

    Affiliations: Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan

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  • Nobutaka Hattori,

    Affiliations: CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan, Department of Neurology, Juntendo University Graduate School of Medicine, Tokyo, Japan

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  • Yuzuru Imai mail,

    yzimai@juntendo.ac.jp (YI); bingwei@stanford.edu (BL)

    Affiliation: Department of Neuroscience for Neurodegenerative Disorders, Juntendo University Graduate School of Medicine, Tokyo, Japan

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  • Bingwei Lu mail

    yzimai@juntendo.ac.jp (YI); bingwei@stanford.edu (BL)

    Affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Published: March 01, 2012
  • DOI: 10.1371/journal.pgen.1002537

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