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Research Article

Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway

  • Kenichiro Taniguchi,

    Affiliation: Department of Biochemistry and Molecular Genetics and Center for Cell Signaling, University of Virginia, Charlottesville, Virginia, United States of America

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  • Anoush E. Anderson,

    Affiliation: Department of Biochemistry and Molecular Genetics and Center for Cell Signaling, University of Virginia, Charlottesville, Virginia, United States of America

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  • Ann E. Sutherland,

    Affiliation: Department of Cell Biology, University of Virginia, Charlottesville, Virginia, United States of America

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  • David Wotton mail

    dw2p@virginia.edu

    Affiliation: Department of Biochemistry and Molecular Genetics and Center for Cell Signaling, University of Virginia, Charlottesville, Virginia, United States of America

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  • Published: February 23, 2012
  • DOI: 10.1371/journal.pgen.1002524

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