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Research Article

Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

  • Jingyuan Fu mail,

    fjingyuan@gmail.com (JF); lude@ludesign.nl (LF)

    Affiliations: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Marcel G. M. Wolfs,

    Affiliation: Department of Pathology and Medical Biology, Molecular Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Patrick Deelen,

    Affiliation: Hanze University Groningen, Groningen, The Netherlands

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  • Harm-Jan Westra,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Rudolf S. N. Fehrmann,

    Affiliations: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Gerard J. te Meerman,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Wim A. Buurman,

    Affiliation: Department of Surgery, University Hospital Maastricht and Nutrition and Toxicology Research Institute (NUTRIM), Maastricht University, Maastricht, The Netherlands

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  • Sander S. M. Rensen,

    Affiliation: Department of Surgery, University Hospital Maastricht and Nutrition and Toxicology Research Institute (NUTRIM), Maastricht University, Maastricht, The Netherlands

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  • Harry J. M. Groen,

    Affiliation: Department of Pulmonology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands

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  • Rinse K. Weersma,

    Affiliation: Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Leonard H. van den Berg,

    Affiliation: Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands

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  • Jan Veldink,

    Affiliation: Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands

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  • Roel A. Ophoff,

    Affiliation: Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands

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  • Harold Snieder,

    Affiliation: Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • David van Heel,

    Affiliation: Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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  • Ritsert C. Jansen,

    Affiliation: Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands

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  • Marten H. Hofker,

    Affiliation: Department of Pathology and Medical Biology, Molecular Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Cisca Wijmenga,

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Lude Franke mail

    fjingyuan@gmail.com (JF); lude@ludesign.nl (LF)

    Affiliation: Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Published: January 19, 2012
  • DOI: 10.1371/journal.pgen.1002431

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