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Research Article

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection

  • Yongsheng Huang,

    Affiliations: Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Statistics, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Aimee K. Zaas,

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Medicine, Duke University, Durham, North Carolina, United States of America

    X
  • Arvind Rao,

    Affiliation: Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

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  • Nicolas Dobigeon,

    Affiliation: IRIT/INP-ENSEEIHT, University of Toulouse, Toulouse, France

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  • Peter J. Woolf,

    Affiliations: Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Timothy Veldman,

    Affiliation: Department of Medicine, Duke University, Durham, North Carolina, United States of America

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  • N. Christine Øien,

    Affiliation: Department of Medicine, Duke University, Durham, North Carolina, United States of America

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  • Micah T. McClain,

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Medicine, Duke University, Durham, North Carolina, United States of America

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  • Jay B. Varkey,

    Affiliation: Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America

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  • Bradley Nicholson,

    Affiliation: Department of Medicine, Duke University, Durham, North Carolina, United States of America

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  • Lawrence Carin,

    Affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, United States of America

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  • Stephen Kingsmore,

    Affiliation: Center for Pediatric Genomic Medicine, Children's Mercy Hospital, Kansas City, Missouri, United States of America

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  • Christopher W. Woods,

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Medicine, Duke University, Durham, North Carolina, United States of America

    X
  • Geoffrey S. Ginsburg mail,

    geoffrey.ginsburg@duke.edu (GSG); hero@eecs.umich.edu (AOH)

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Medicine, Duke University, Durham, North Carolina, United States of America

    X
  • Alfred O. Hero III mail

    geoffrey.ginsburg@duke.edu (GSG); hero@eecs.umich.edu (AOH)

    Affiliations: Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Statistics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Published: August 25, 2011
  • DOI: 10.1371/journal.pgen.1002234

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