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Research Article

PTG Depletion Removes Lafora Bodies and Rescues the Fatal Epilepsy of Lafora Disease

  • Julie Turnbull,

    Affiliations: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada

    X
  • Anna A. DePaoli-Roach mail,

    berge.minassian@sickkids.ca (BAM); adepaoli@iupui.edu (AAD-R)

    Affiliation: Department of Biochemistry and Molecular Biology, Indiana University, Indianapolis, Indiana, United States of America

    X
  • Xiaochu Zhao,

    Affiliation: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada

    X
  • Miguel A. Cortez,

    Affiliation: Division of Neurology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada

    X
  • Nela Pencea,

    Affiliations: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada, Department of Pathology and Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada

    X
  • Erica Tiberia,

    Affiliation: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada

    X
  • Mark Piliguian,

    Affiliation: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada

    X
  • Peter J. Roach,

    Affiliation: Department of Biochemistry and Molecular Biology, Indiana University, Indianapolis, Indiana, United States of America

    X
  • Peixiang Wang,

    Affiliation: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada

    X
  • Cameron A. Ackerley,

    Affiliation: Department of Pathology and Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada

    X
  • Berge A. Minassian mail

    berge.minassian@sickkids.ca (BAM); adepaoli@iupui.edu (AAD-R)

    Affiliations: Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada, Division of Neurology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada

    X
  • Published: April 28, 2011
  • DOI: 10.1371/journal.pgen.1002037

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