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Research Article

Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome

  • Toshiyuki Bohgaki equal contributor,

    equal contributor Contributed equally to this work with: Toshiyuki Bohgaki, Miyuki Bohgaki

    Affiliation: Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada

    X
  • Miyuki Bohgaki equal contributor,

    equal contributor Contributed equally to this work with: Toshiyuki Bohgaki, Miyuki Bohgaki

    Affiliation: Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada

    X
  • Renato Cardoso,

    Affiliation: Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada

    X
  • Stephanie Panier,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

    X
  • Dimphy Zeegers,

    Affiliation: Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    X
  • Li Li,

    Affiliation: Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada

    X
  • Grant S. Stewart,

    Affiliation: Cancer Research UK, Institute for Cancer Studies, Birmingham University, Birmingham, United Kingdom

    X
  • Otto Sanchez,

    Affiliation: University of Ontario Institute of Technology, Oshawa, Canada

    X
  • M. Prakash Hande,

    Affiliation: Cancer Research UK, Institute for Cancer Studies, Birmingham University, Birmingham, United Kingdom

    X
  • Daniel Durocher,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

    X
  • Anne Hakem mail,

    ahakem@uhnres.utoronto.ca (AH); rhakem@uhnres.utoronto.ca (RH)

    Affiliation: Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada

    X
  • Razqallah Hakem mail

    ahakem@uhnres.utoronto.ca (AH); rhakem@uhnres.utoronto.ca (RH)

    Affiliation: Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada

    X
  • Published: April 28, 2011
  • DOI: 10.1371/journal.pgen.1001381

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