Advertisement
Research Article

Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA

  • Julia Ling-Yu Chen,

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America

    X
  • Daniel Merl,

    Affiliation: Department of Statistical Science, Duke University, Durham, North Carolina, United States of America

    X
  • Christopher W. Peterson,

    Affiliation: Huntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Jianli Wu,

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America

    X
  • Patrick Yantyng Liu,

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America, Department of Medicine, National Yang-Ming University, Taipei, Taiwan

    X
  • Hanwei Yin,

    Affiliation: Huntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Deborah M. Muoio,

    Affiliation: Sarah W. Stedman Nutrition and Metabolism Center, Department of Pharmacology and Cancer Biology and Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Don E. Ayer,

    Affiliation: Huntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Mike West,

    Affiliation: Department of Statistical Science, Duke University, Durham, North Carolina, United States of America

    X
  • Jen-Tsan Chi mail

    chi00002@mc.duke.edu

    Affiliations: Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America

    X
  • Published: September 02, 2010
  • DOI: 10.1371/journal.pgen.1001093

Reader Comments (0)

Post a new comment on this article